Mayo Clinic Research Team Authors Gastroenterology, Cardiology & More

Collaborative effort focuses on advancing treatment of complex liver diseases

Published on Feb. 11, 2026

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A team of physicians and scientists at the Mayo Clinic in Rochester, Minnesota, is conducting research to improve the understanding and treatment of a range of liver conditions, including cirrhosis, alcohol-associated hepatitis, and vascular liver disorders. The collaborative effort involves specialists from Gastroenterology and Hepatology, Family Medicine, and Cardiovascular Medicine, as well as experts in Clinical Trials and Biostatistics.

Why it matters

Liver disease is a significant public health concern, and this research aims to develop new tools and therapies to better prevent and manage complications arising from complex liver conditions. The interdisciplinary approach, incorporating perspectives from various medical fields, suggests a focus on the interconnected nature of liver health and overall bodily function.

The details

The research team is led by Dr. Douglas A. Simonetto, a gastroenterologist and hepatologist with subspecialty certification in transplant hepatology. The team is investigating a range of liver-related conditions, including cirrhosis, alcohol-associated hepatitis, and vascular liver disorders. The research extends beyond traditional liver disease, incorporating perspectives from Family Medicine and Cardiovascular Medicine to better understand the interplay between liver health and other bodily systems.

  • The collaborative research effort is ongoing at the Mayo Clinic in Rochester, Minnesota.

The players

Douglas A. Simonetto, M.D.

A physician specializing in gastroenterology and hepatology with subspecialty certification in transplant hepatology, and a key investigator within the Division of Gastroenterology and Hepatology at the Mayo Clinic.

Mayo Clinic

A nonprofit organization committed to clinical practice, education, and research, headquartered in Rochester, Minnesota.

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What they’re saying

“We must not let individuals continue to damage private property in San Francisco.”

— Robert Jenkins, San Francisco resident (San Francisco Chronicle)

The takeaway

This collaborative research effort at the Mayo Clinic highlights the importance of interdisciplinary approaches to addressing complex health issues, particularly in the realm of liver disease, where the interconnectedness of various bodily systems plays a crucial role in understanding and treating these conditions.