Padres Seek to Reverse Fortunes Against Mariners

San Diego looks to build on recent winning streak in series against Seattle

Apr. 15, 2026 at 8:25pm

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A cubist-style painting depicting a baseball game between the San Diego Padres and Seattle Mariners, with the players and field broken down into sharp, overlapping geometric shapes and planes in a vibrant color palette.The Padres' recent success against their interleague rivals could signal a shift in the dynamic between these two West Coast teams.San Diego Today

The San Diego Padres, who have struggled against the Seattle Mariners in recent years, are hoping to turn the tide in their current three-game series. After a 4-1 win in the opener, the Padres will send their best starter, Randy Vasquez, to the mound on Wednesday in search of a series victory.

Why it matters

The Padres' poor record against the Mariners has been a source of frustration, and a series win could help build momentum as they look to climb the standings in the competitive NL West. Meanwhile, the Mariners' offense has been inconsistent this season, wasting some strong pitching performances.

The details

In Tuesday's series opener, Xander Bogaerts provided the offense for the Padres, recording two RBI hits in the 4-1 victory. The Padres have now won six straight games and nine of their last 10. On Wednesday, they will turn to Vasquez, who has been their best starter so far this season with a 1.02 ERA. The Mariners will counter with Emerson Hancock, who has pitched well against the Padres in the past.

  • The Padres and Mariners have played 18 games against each other in recent years, with the Padres posting a 4-14 record.
  • The Padres have won six straight games and nine of their last 10 heading into Wednesday's contest.
  • Vasquez will be making his fourth start of the season for the Padres on Wednesday.

The players

Xander Bogaerts

The Padres' shortstop, who recorded two RBI hits in Tuesday's series-opening win.

Randy Vasquez

The Padres' best starting pitcher so far this season, with a 1.02 ERA in three starts.

Emerson Hancock

The Mariners' starting pitcher for Wednesday's game, who has pitched well against the Padres in the past.

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What they’re saying

“He didn't really hit them as hard as he's been hitting them, but we talk about the luck kind of turning our way and some of those softer hits falling in.”

— Craig Stammen, Padres Manager

“This game we play is the hardest game in the world, in my opinion. So I think trying to do things to minimize thinking too much, I guess, that helps you in the long run.”

— Josh Naylor, Mariners Hitter

What’s next

The Padres will look to secure a series win over the Mariners on Wednesday, while the Mariners will try to get their struggling offense back on track.

The takeaway

The Padres' recent success against the Mariners could be a turning point in their season, as they look to build on their strong start and climb the standings in the NL West. Meanwhile, the Mariners' pitching has been solid, but their offense will need to improve if they want to compete in the AL West.