Actress Christina Applegate Speaks Out on Living with MS

The star continues to be transparent about her experience with the chronic disease.

Apr. 17, 2026 at 2:58pm

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A glowing neon outline of a human brain against a dark background, conceptually representing the neurological impacts of multiple sclerosis.Actress Christina Applegate's candid discussions about living with multiple sclerosis have helped raise awareness about the realities of this complex neurological condition.Salt Lake City Today

Two years after revealing her multiple sclerosis diagnosis, actress Christina Applegate has remained open about her journey with the chronic autoimmune disease. The Salt Lake City native has been vocal about how she wants to spend her remaining time, focusing on quality of life and cherishing each moment.

Why it matters

Applegate's candid discussions about her MS diagnosis and treatment have helped raise awareness about the realities of living with this complex neurological condition, which can significantly impact a person's mobility, cognition, and overall wellbeing.

The details

Since going public with her MS diagnosis in 2020, Applegate has been outspoken about the physical and emotional challenges she faces. The 51-year-old actress has shared details about how the disease has affected her daily life and the adjustments she's had to make to adapt to her 'new normal'.

  • Applegate revealed her multiple sclerosis diagnosis in August 2020.

The players

Christina Applegate

A 51-year-old American actress known for her roles in television shows like 'Married... with Children' and films such as 'Anchorman' and 'Bad Moms'. She was diagnosed with multiple sclerosis in 2020.

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What they’re saying

“I'm trying to find my way through all of this and it's going to take time. I do have MS and I'm not ashamed of that. It's something I deal with every day.”

— Christina Applegate, Actress

The takeaway

Applegate's openness about her multiple sclerosis journey has helped destigmatize the disease and inspired others living with chronic illnesses to be more vocal about their experiences. Her story underscores the importance of raising awareness and providing support for those affected by MS.