Kelly Osbourne Addresses 'Ozempic Face' Rumors After Dramatic Weight Loss

The reality star opens up about her weight loss journey and the public scrutiny she faces.

Published on Feb. 15, 2026

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Photographs of Kelly Osbourne's dramatic transformation have sparked widespread discussion about the use of weight loss medications like Ozempic and the resulting 'Ozempic face' phenomenon. While some have speculated about Osbourne's use of such drugs, the reality star has publicly attributed her 85-pound weight loss to dietary changes following the birth of her son in 2022. Osbourne has also addressed the public scrutiny she faces regarding her body image, revealing the longstanding pressures she has experienced in the entertainment industry.

Why it matters

The conversation surrounding Osbourne's weight loss highlights the complex relationship between societal pressures, body image, and the pursuit of rapid weight loss. As the use of medications like Ozempic for weight loss becomes more prevalent, understanding the potential side effects, including facial changes, is crucial. Osbourne's experience also underscores the ongoing challenges celebrities face regarding public commentary on their appearance.

The details

Photographs of Kelly Osbourne spanning from 2019 to 2026 reveal a more gaunt facial structure in her recent photos, characterized by prominent cheekbones, a defined jawline, and a noticeable loss of facial volume. This transformation has fueled speculation about the methods behind her weight loss, particularly the use of medications like Ozempic. However, Osbourne has publicly stated that Ozempic played no role in her weight loss, attributing her success to eliminating sugar and carbohydrates from her diet.

  • In April 2024, Osbourne told Extra that Ozempic was not a factor in her 85-pound weight loss.
  • In February 2024, Osbourne expressed support for individuals who choose to use Ozempic for weight loss in an interview with E! News.
  • In December 2025, Osbourne directly confronted comments about her appearance and alleged Ozempic use in a since-deleted Instagram video, as reported by USA Today.

The players

Kelly Osbourne

A reality TV star who has faced public scrutiny regarding her body image and weight loss journey.

Vinni Makin, MD

An endocrinologist at the Cleveland Clinic who explained the characteristics of 'Ozempic face.'

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What they’re saying

“My dad just died, and I'm doing the best that I can, and the only thing I have to live for right now is my family.”

— Kelly Osbourne (USA Today)

“It's characterized by gauntness, sunken cheeks, new wrinkles and loose skin on the face and neck.”

— Vinni Makin, MD, Endocrinologist, Cleveland Clinic (archyde.com)

What’s next

As the use of weight loss medications like Ozempic continues to rise, further research is needed to fully understand the long-term effects on facial structure and overall health. The focus will likely shift towards developing strategies to mitigate potential side effects and promote healthy, sustainable weight management practices.

The takeaway

Kelly Osbourne's experience highlights the complex relationship between societal pressures, body image, and the pursuit of rapid weight loss. While the discussion surrounding 'Ozempic face' raises important questions, Osbourne's journey underscores the ongoing challenges celebrities face regarding public commentary on their appearance and the need for a more compassionate approach to discussing weight and health.