Lena Dunham Reflects on Relationship with Jack Antonoff in New Memoir

The actress and writer opens up about how her health struggles impacted her romance with the musician.

Apr. 14, 2026 at 1:21pm

An abstract close-up image of shattered glass and glittering sequins, capturing the fragility and glamour of celebrity relationships.Dunham's memoir 'Famesick' offers a raw, honest look at the challenges of maintaining a relationship amid personal health crises.NYC Today

In her new memoir 'Famesick', Lena Dunham reflects on her past relationships, including her romance with musician Jack Antonoff. Dunham details how navigating her chronic health issues, including a diagnosis of endometriosis and a subsequent hysterectomy, took a toll on her relationship with Antonoff, which ended shortly after her surgery in 2017. Though Dunham describes Antonoff as a 'good man', she acknowledges her own role in the relationship's unraveling, saying 'You realize there's a common denominator issue here.'

Why it matters

Dunham's candid account of her relationship challenges sheds light on the difficulties that can arise when chronic illness impacts a romantic partnership. Her willingness to examine her own part in the relationship's demise also demonstrates a level of self-awareness that many public figures struggle to achieve when discussing their personal lives.

The details

In 'Famesick', Dunham writes about the end of her six-year relationship with Antonoff, noting that 'Looking back, it's hard to understand why two people with seemingly endless options, financial freedom and almost nothing that they still enjoyed doing together besides talking s--- about the occasional third party would not simply break up.' She says the relationship persisted even as it struggled, with the two feeling that 'our ability to keep the relationship going was directly proportional to our inherent goodness.' Dunham's health issues, including her endometriosis diagnosis at age 26 and subsequent hysterectomy in 2017, took a significant toll, with the relationship ending shortly after the surgery.

  • Dunham and Antonoff dated from 2012 to 2017.
  • Dunham was diagnosed with endometriosis at age 26.
  • Dunham had a hysterectomy in 2017 after her endometriosis caused extensive damage.
  • Dunham's relationship with Antonoff ended almost immediately following her hysterectomy.

The players

Lena Dunham

A 39-year-old actress, writer, and director who is reflecting on her past relationships, including her six-year romance with musician Jack Antonoff, in her new memoir 'Famesick'.

Jack Antonoff

A musician who dated Dunham from 2012 to 2017. Dunham describes him as a 'good man' but acknowledges her own role in the relationship's unraveling.

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What they’re saying

“You can have really beautiful relationships that don't work”

— Lena Dunham

“My hope is that whoever is reading understands that it's not a victim narrative and it's not a narrative in which there are wrongdoers”

— Lena Dunham

The takeaway

Dunham's willingness to examine her own role in the unraveling of her relationship with Antonoff, even as she navigated significant health challenges, demonstrates a level of self-awareness and responsibility that is often lacking in celebrity memoirs. Her story highlights the complexities that can arise when chronic illness impacts a romantic partnership.