Chamber Raises $60 Million in Series A Funding

Funding will support expansion of value-based cardiology care platform

Published on Feb. 5, 2026

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Chamber, a company focused on supporting cardiologists and health plans in managing patients with heart disease under value-based care models, has raised $60 million in Series A funding. The round was led by Frist Cressey Ventures, with participation from investors including General Catalyst, Optum Ventures, and Healthworx Ventures. The funding will be used to expand partnerships, grow into new markets, and continue building Chamber's clinical, operational, and technology teams.

Why it matters

Cardiovascular disease is a major driver of healthcare costs in the U.S., yet care delivery remains fragmented and fee-for-service-driven. Chamber's platform aims to bring value-based care to cardiology, delivering better outcomes and improved quality of life for patients.

The details

Chamber's cardiology-focused data and intelligence platform integrates workflow-native AI to prioritize high-risk patients, identify gaps in guideline-directed therapy, and reduce manual chart review. This, combined with Chamber's operational infrastructure, helps reduce preventable complications and hospital use, improve patient experience, and provide health plans with clearer visibility into cardiovascular performance and total cost of care.

  • Chamber announced the $60 million Series A funding on February 4, 2026.

The players

Chamber

A company dedicated to supporting cardiology practices through technology-enabled delivery, co-founded by healthcare industry leaders George Aloth, Dr. Sameer Sheth, and Dr. Jeffrey De Flavio.

Frist Cressey Ventures

The venture capital firm that led Chamber's Series A funding round.

General Catalyst

An investment firm that participated in Chamber's Series A funding round.

Optum Ventures

The venture capital arm of UnitedHealth Group that participated in Chamber's Series A funding round.

Healthworx Ventures

The venture capital arm of CareFirst BlueCross BlueShield that participated in Chamber's Series A funding round.

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What’s next

Chamber plans to continue expanding its partnerships with health plans and cardiology practices, as well as growing into additional markets across the country.

The takeaway

Chamber's platform aims to transform cardiology care delivery by bringing value-based care models to a field that has historically been dominated by fee-for-service reimbursement. This has the potential to improve patient outcomes, reduce healthcare costs, and provide cardiologists with the tools and support they need to succeed in a changing healthcare landscape.