No DNA Matches Found on Glove Near Missing Arizona Woman's Home

Police continue to investigate the disappearance of Nancy Guthrie, mother of Today host Savannah Guthrie.

Published on Feb. 21, 2026

Pima County sheriff's department confirmed that no DNA matches were found in the FBI database from a glove discovered two miles from the home of missing 84-year-old Nancy Guthrie in Tucson, Arizona. The glove, which appeared to match one worn by a masked suspect seen on doorbell camera footage, contained an unknown male DNA profile. Despite this setback, authorities say the investigation remains active as they continue to pursue leads in Guthrie's disappearance.

Why it matters

The lack of DNA matches on the glove is a significant development in the high-profile case of Nancy Guthrie's disappearance, which has garnered national attention as the mother of Today show host Savannah Guthrie. While disappointing, the sheriff's department remains committed to finding answers and the perpetrator, underscoring the challenges law enforcement can face in cracking complex missing persons cases.

The details

A potential break in the case came last week when law enforcement discovered a glove in desert shrubbery about two miles from Guthrie's home. The black glove appeared to match one worn by the masked individual seen in the doorbell camera footage and contained an unknown male DNA profile. However, on Tuesday (February 17), Pima County Sheriff Chris Nanos told Fox News that no matches were found in the FBI's DNA database after the sample was analyzed. Nanos also said DNA recovered from Guthrie's home (different from the DNA on the glove) also didn't match any records in the FBI database.

  • Nancy Guthrie went missing on January 31.
  • The glove was discovered last week, about two miles from Guthrie's home.
  • On February 17, authorities confirmed the glove's DNA did not match any records in the FBI database.

The players

Nancy Guthrie

An 84-year-old woman who went missing from her home in Tucson, Arizona on January 31. She is the mother of Today show host Savannah Guthrie.

Chris Nanos

The Pima County Sheriff in Arizona, who has been leading the investigation into Nancy Guthrie's disappearance.

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What they’re saying

“As long as we have the ability to chase a lead, it's not cold. We're not going to give up. We're going to find Nancy, and we're going to find out who did this.”

— Chris Nanos, Pima County Sheriff (NBC News)

What’s next

The Pima County Sheriff's Department says it will continue analyzing DNA evidence and pursuing all leads in the investigation into Nancy Guthrie's disappearance.

The takeaway

The lack of DNA matches on the glove found near Nancy Guthrie's home is a setback, but authorities remain committed to finding answers and the perpetrator in this high-profile missing persons case. The challenges of cracking complex cases without clear forensic evidence underscore the need for perseverance and innovative investigative techniques by law enforcement.