Brewers Host Nationals in Interleague Matchup

Woodruff and Littell set to take the mound as Milwaukee looks to extend home win streak

Apr. 12, 2026 at 1:18pm

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A cubist, geometric painting depicting a baseball game, with players and the field broken down into sharp, overlapping shapes and planes of color.The Brewers and Nationals square off in a pivotal interleague matchup, with both teams looking to gain ground in the playoff race.Today in Milwaukee

The Milwaukee Brewers (-200) host the Washington Nationals (+165) in an interleague matchup at American Family Field on April 12, 2026. The Brewers, led by starting pitcher Brandon Woodruff (1-0, 5.91 ERA), look to continue their strong start at home against the struggling Nationals and starter Zack Littell (0-1, 3.60 ERA).

Why it matters

This game features two teams heading in opposite directions early in the season. The Brewers have been dominant at home, while the Nationals have struggled on the road. The outcome could have implications for the NL Central and Wild Card races as the season progresses.

The details

The Brewers enter this game 9-5 against the spread this season, while the Nationals are 6-8 ATS. Milwaukee has been particularly strong when scoring 5 or more runs, going 79-7 (.919) in those games since 2025. Conversely, the Nationals have struggled when their opponents score in the first inning, going just 12-46 (.203) in those situations since 2025.

  • The first pitch is scheduled for 2:10 pm local time in Milwaukee, Wisconsin.

The players

Brandon Woodruff

The Brewers' starting pitcher, who is 1-0 with a 5.91 ERA so far this season.

Zack Littell

The Nationals' starting pitcher, who is 0-1 with a 3.60 ERA this season.

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What they’re saying

“We must not let individuals continue to damage private property in San Francisco.”

— Robert Jenkins, San Francisco resident

“Fifty years is such an accomplishment in San Francisco, especially with the way the city has changed over the years.”

— Gordon Edgar, grocery employee

The takeaway

This game features two teams heading in opposite directions, with the Brewers looking to continue their strong start at home and the Nationals trying to turn things around on the road. The outcome could have significant implications for the playoff races in both the NL Central and Wild Card.