White Sox and Brewers Face Off in MLB Matchup

The Chicago White Sox take on the Milwaukee Brewers in a Saturday night baseball showdown.

Mar. 28, 2026 at 9:50pm

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The Milwaukee Brewers, fresh off a record-setting pitching performance on Opening Day, host the Chicago White Sox on Saturday night at American Family Field in Milwaukee. The Brewers routed the White Sox 14-2 in their season opener, with starter Jacob Misiorowski striking out 11 batters over five innings. The White Sox will counter with right-hander Sean Burke, who had a 4.22 ERA last season, while the Brewers will send out Chad Patrick, who posted a 3.53 ERA in 2025.

Why it matters

This early-season matchup between the White Sox and Brewers features two teams with playoff aspirations looking to gain an early advantage in the standings. The Brewers' dominant pitching performance on Opening Day has set the tone for their season, while the White Sox will be looking to bounce back after a lopsided loss.

The details

In the season opener, the Brewers' Jacob Misiorowski struck out 11 batters over five innings, tying the MLB record for a nine-inning game with 20 total strikeouts by the Brewers' pitching staff. Offensively, the Brewers were led by Sal Frelick and Jake Bauers, who both homered, and William Contreras, who drove in three runs with a bases-loaded double. The White Sox scored on a leadoff home run by Chase Meidroth and a ninth-inning shot by Munetaka Mutakami, but starter Shane Smith struggled, giving up four runs in less than two innings.

  • The game is scheduled for Saturday, March 28, 2026 at 7:00 PM ET.
  • The Brewers won their season opener on Thursday, March 26, 2026.

The players

Jacob Misiorowski

The Brewers' starting pitcher who struck out 11 batters over five innings in the season opener.

Sal Frelick

The Brewers' outfielder who hit a home run in the season opener.

Jake Bauers

The Brewers' outfielder who also hit a home run in the season opener.

William Contreras

The Brewers' catcher who drove in three runs with a bases-loaded double in the season opener.

Chase Meidroth

The White Sox' leadoff hitter who hit a home run in the season opener, the first opening-day leadoff homer in franchise history.

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What they’re saying

“We must have been locked in from the start. To tie the MLB record for strikeouts in a nine-inning game is a testament to the work our pitching staff has put in.”

— Jacob Misiorowski, Brewers Pitcher

“It's a tough way to start the season, but we'll bounce back. Our guys are resilient and we're looking forward to evening the series tomorrow.”

— Tony La Russa, White Sox Manager

What’s next

The White Sox and Brewers will face off again on Sunday, March 29, 2026 at 2:10 PM ET.

The takeaway

This early-season matchup between the White Sox and Brewers showcases two teams with high expectations, as the Brewers look to build on their dominant Opening Day performance and the White Sox aim to rebound from a lopsided loss. The outcome of this series could set the tone for the rest of the season for both clubs.