Janesville Facility Receives $263M DOE Loan for Medical Isotope Production

SHINE Chrysalis project aims to boost domestic supply of critical medical isotopes.

Apr. 9, 2026 at 10:50pm

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An abstract painting in soft, earthy tones of green, brown, and blue, featuring sweeping geometric arcs, concentric circles, and precise botanical spirals, conceptually representing the complex particle accelerator technology and isotope production process at a new facility in Janesville.A major federal investment will help bring advanced isotope production technology to Janesville, solidifying the city's role as a hub for nuclear innovation.Janesville Today

The U.S. Department of Energy has issued a conditional commitment for a loan of up to $263 million to SHINE Chrysalis, a company building a high-volume medical isotope production facility in Janesville, Wisconsin. The project aims to increase the domestic supply of critical medical isotopes used in diagnostic imaging and cancer treatment.

Why it matters

Medical isotopes are in high demand globally, but the U.S. currently relies heavily on imports. This new facility in Janesville could help reduce American dependence on foreign suppliers and ensure a more reliable, domestic source of these essential medical materials.

The details

SHINE Chrysalis is constructing a state-of-the-art facility in Janesville that will use innovative technology to produce large quantities of medical isotopes like molybdenum-99 and technetium-99m. These isotopes are widely used in nuclear medicine procedures to diagnose and monitor various health conditions.

  • The DOE issued the conditional loan commitment in April 2026.
  • Construction on the SHINE Chrysalis facility in Janesville began in 2024 and is expected to be completed by 2028.

The players

SHINE Chrysalis

A company building a high-volume medical isotope production facility in Janesville, Wisconsin.

U.S. Department of Energy

The federal agency that has issued a conditional $263 million loan commitment to support the SHINE Chrysalis project.

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What they’re saying

“This project will help ensure a reliable, domestic supply of critical medical isotopes that are essential for diagnosing and treating a wide range of health conditions.”

— Jennifer Granholm, U.S. Secretary of Energy

What’s next

The DOE loan commitment is contingent on SHINE Chrysalis meeting certain milestones and requirements. If approved, construction on the Janesville facility is expected to be completed by 2028.

The takeaway

The SHINE Chrysalis project in Janesville represents a significant investment in domestic medical isotope production, which could help reduce American reliance on foreign suppliers and ensure a more reliable supply of these essential materials for the healthcare system.