Serena Williams Flaunts Dramatic Weight Loss in GLP-1 Super Bowl Ad

The tennis legend teases her upcoming commercial for Ro's GLP-1 medications.

Jan. 30, 2026 at 6:47am

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Serena Williams took to social media to tease her upcoming Super Bowl ad for Ro, a company that sells GLP-1 medications like Ozempic. In the clip, Williams flaunts her dramatic 30-pound weight loss in an ab-baring outfit as a spotlight shines on her. The ad is part of Ro's "Healthier on Ro" campaign to destigmatize GLP-1 drugs and promote their health benefits beyond weight loss.

Why it matters

Serena Williams' weight loss and partnership with Ro have generated significant buzz, as the tennis legend has been open about using GLP-1 medications to shed 30 pounds. This Super Bowl ad will further raise awareness of these types of medications and their potential uses beyond just weight management.

The details

In the teaser clip posted on Instagram, Williams is seen wearing an ab-baring top and pleated skirt as a spotlight dramatically shines on her. The image then spins around to reveal the date of the upcoming Super Bowl matchup between the Seahawks and Patriots. Williams has been an ambassador for Ro, which sells GLP-1 drugs like Ozempic, since late 2025.

  • Williams posted the teaser clip on her Instagram on January 28, 2026.
  • The Super Bowl 60 game featuring the Seahawks and Patriots will take place on February 2, 2026.

The players

Serena Williams

A legendary tennis player who retired in 2022 and has recently been open about using GLP-1 medications to lose 30 pounds.

Ro

A company that sells GLP-1 medications such as Ozempic, and has partnered with Serena Williams as an ambassador for its "Healthier on Ro" campaign.

Alexis Ohanian

Serena Williams' husband, who is an investor in Ro and serves on its board of directors.

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What’s next

The full Super Bowl ad featuring Serena Williams will air during Super Bowl 60 on February 2, 2026.

The takeaway

Serena Williams' partnership with Ro and her openness about using GLP-1 medications to lose weight have generated significant interest and buzz. This Super Bowl ad will further raise awareness of these types of medications and their potential benefits beyond just weight management.