Navigating the Acute Phase of Peyronie's Disease

Experts offer guidance for managing the initial, most challenging stage of this penile condition.

Apr. 1, 2026 at 10:40pm

A diagnosis of Peyronie's disease, characterized by the development of fibrous scar tissue within the penis and often a painful bending during erection, can be deeply distressing for men. Symptoms are most dramatic in the initial acute, or active, phase, followed by a stable phase when the symptoms are less severe. Experts emphasize the importance of seeking treatment in the first 12 months to get the disease under control before it becomes more difficult to manage.

Why it matters

Peyronie's disease can have significant sexual and psychological effects, so understanding how to navigate the acute phase is crucial for men's health and wellbeing. The condition is not well known, so a diagnosis often comes as a shock, making timely treatment and support all the more important.

The details

According to Dr. Travis Green, an assistant professor and urologist at McGovern Medical School at UTHealth Houston, the acute phase of Peyronie's disease is characterized by the development of a noticeable curvature, a palpable lump, and painful erections. These symptoms can be deeply distressing for men who are unfamiliar with the condition.

  • The acute, or active, phase of Peyronie's disease is most dramatic in the first 12 months after symptom onset.
  • After the initial acute phase, the condition enters a stable phase when symptoms are less severe and more manageable.

The players

Travis Green, MD

An assistant professor and urologist at McGovern Medical School at UTHealth Houston who specializes in Peyronie's disease.

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What they’re saying

“Many men have never heard of Peyronie's disease before they develop it, so the diagnosis often comes as a shock.”

— Travis Green, MD, Assistant Professor and Urologist

“Seeing a new curvature, feeling a lump, or experiencing pain during erections can be alarming and deeply distressing.”

— Travis Green, MD, Assistant Professor and Urologist

What’s next

Experts recommend that men seek treatment for Peyronie's disease as soon as possible, within the first 12 months of symptom onset, in order to get the condition under control before it becomes more difficult to manage.

The takeaway

Peyronie's disease can have a significant impact on men's sexual and psychological wellbeing, so understanding how to navigate the acute, most challenging phase of the condition is crucial. Seeking timely treatment and support is key to managing the disease and minimizing its effects.