Pomegranate Peel Packs Antiviral Punch Against Flu

Studies show compounds in the fruit may disrupt flu virus infection.

Published on Feb. 6, 2026

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Researchers have found that punicalagin, a compound found in pomegranates, can disrupt the process by which the flu virus infects human cells. This suggests pomegranates and their peels may offer an additional layer of protection against influenza, especially in years when flu vaccine efficacy is lower.

Why it matters

With this year's flu season hitting New York City particularly hard, and concerns over lower than usual vaccine efficacy, finding natural ways to boost immunity is crucial. Pomegranates have long been revered for their healing properties, and the new research indicates they may be a valuable tool in the fight against the flu.

The details

A study out of Iran found that punicalagin, a compound in pomegranates, can disrupt the process of hemagglutination, or the clumping together of red blood cells, which is how the flu virus infects human cells. The researchers concluded that 'punicalagin was effective against influenza infection.' Pomegranates have also shown antimicrobial benefits against other illnesses like herpes, E. coli, and HIV-1.

  • The study out of Iran was published in 2026.

The players

Punicalagin

A compound found in pomegranates that has demonstrated antiviral properties, particularly against the influenza virus.

Shannon Haynes, RD

A registered dietitian with Hartford HealthCare at Backus Hospital who recommends adding pomegranate to one's diet for its many health benefits.

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What they’re saying

“Pomegranate is one of those fruits that does a lot of good for your body — heart, skin, and digestion, to name just a few. It's packed with antioxidants, vitamins and fiber. And it tastes really good, too.”

— Shannon Haynes, Registered Dietitian (Hartford HealthCare at Backus Hospital)

What’s next

Researchers are calling for more testing on in vivo human subjects, as opposed to in vitro cells, to further understand pomegranate's antiviral effects against the flu.

The takeaway

With flu season hitting hard and vaccine efficacy a concern, pomegranates may provide an additional natural defense against influenza. Incorporating pomegranate and its nutrient-rich peel into one's diet could be a simple way to boost immunity this winter.