Celebrities, AI, and Weight-Loss Drugs Dominate Super Bowl 60 Ads

From Kendall Jenner to George Clooney, this year's Super Bowl commercials feature a star-studded lineup and emerging tech trends.

Feb. 5, 2026 at 7:39pm

Got story updates? Submit your updates here. ›

As Super Bowl 60 approaches, advertisers are pulling out all the stops to capture the attention of the over 120 million viewers expected to tune in. This year's trends include a heavy focus on health and telehealth companies advertising weight loss drugs and medical tests, tech companies showcasing their latest AI-powered gadgets and apps, and a star-studded lineup of celebrity cameos from the likes of Kendall Jenner, George Clooney, and more. Advertisers are also sticking to a light, escapist tone to help viewers take a break from the heavy news cycle.

Why it matters

Super Bowl ads offer a unique window into the American zeitgeist, reflecting the industries and cultural trends that are top of mind for consumers. This year's lineup highlights the growing influence of the health and tech sectors, as well as the continued power of celebrity endorsements to drive brand engagement. The prevalence of weight loss drug ads also speaks to the public's ongoing struggles with health and wellness.

The details

Dozens of advertisers are aiming to make a splash during Super Bowl 60, with 30-second ad spots selling for an average of $8 million, a new record. Trends include a heavy focus on health and telehealth, with companies like Novartis, Boehringer Ingelheim, Liquid I.V., Ro, and Hims & Hers advertising medical tests and weight loss drugs. Tech companies are also showcasing their latest AI-powered innovations, with ads from Oakley Meta, Wix, and OpenAI. And the celebrity-packed lineup includes Kendall Jenner, George Clooney, Kurt Russell, Lewis Pullman, Chloe Kim, T.J. Oshie, Sam Neill, Laura Dern, Jeff Goldblum, Matthew McConaughey, Bradley Cooper, and Parker Posey.

  • Super Bowl 60 will air on Sunday, February 11, 2026.

The players

Kendall Jenner

A model and media personality who will appear in a Fanatics Sportsbook ad discussing the "Kardashian Kurse."

George Clooney

An actor who will appear in a Grubhub ad promoting a deal that the delivery app offers to "Eat the Fees" on orders of $50 or more.

Novartis

A pharmaceutical company that is advertising a blood test to screen for prostate cancer with the tagline "Relax your tight end."

Boehringer Ingelheim

A pharmaceutical company that is advertising a kidney disease screening test starring Octavia Spencer and Sofia Vergara.

Ro

A telehealth firm that is using Serena Williams in their ad for GLP-1 weight loss drugs.

Got photos? Submit your photos here. ›

What they’re saying

“Because of the Super Bowl's status as a pop culture event with a fun party atmosphere, the vast majority of brands will avoid any dark or divisive tone and instead allow consumers to escape from thinking about these troubled times.”

— Charles Taylor, Marketing professor, Villanova University

“You could call this the GLP-1 Super Bowl. Often you don't see a lot from pharmaceutical companies on the Super Bowl, but this year we're going to see quite a few showing up.”

— Tim Calkins, Clinical professor of marketing, Northwestern University

What’s next

Viewers will have to tune in on Super Bowl Sunday, February 11, 2026, to see how the highly anticipated ads perform and which ones generate the most buzz.

The takeaway

This year's Super Bowl ad lineup reflects the growing influence of the health and tech sectors, as well as the continued power of celebrity endorsements to drive brand engagement. The prevalence of weight loss drug ads also speaks to the public's ongoing struggles with health and wellness, underscoring the need for balanced, holistic approaches to wellbeing.