St. Louis Police Renew Appeal In Dwayne Wysinger Killing

Federal indictments filed in 2024, but detectives still seek leads in 2021 fatal shooting

Published on Feb. 8, 2026

The St. Louis Metropolitan Police Department (SLMPD) has renewed its appeal for public information regarding the 2021 killing of 18-year-old Dwayne Wysinger. Wysinger was found shot next to a vehicle in the Peabody-Darst-Webbe neighborhood and was pronounced dead at the scene. Federal prosecutors reported that two St. Louis men were indicted in 2024 on charges including conspiracy to commit murder-for-hire and murder-for-hire in connection with Wysinger's death, but detectives continue to investigate the unsolved homicide and are seeking additional tips from the public.

Why it matters

Wysinger's killing has remained unsolved despite federal indictments, highlighting the challenges law enforcement can face in obtaining sufficient evidence to prosecute complex murder cases, even with charges filed. The renewed appeal for public assistance underscores the importance of community cooperation in helping to solve violent crimes.

The details

According to the U.S. Attorney's Office for the Eastern District of Missouri, the federal indictment claims that the suspects were allegedly informed of a bounty on Wysinger and waited to ambush him. The charges are allegations, and the defendants are presumed innocent until proven guilty. Police found Wysinger with a gunshot wound to his upper body near a vehicle showing bullet damage on the night of August 14, 2021, in the Peabody-Darst-Webbe neighborhood. He was pronounced dead at the scene.

  • Wysinger was killed on August 14, 2021.
  • Federal indictments were filed on May 8, 2024.

The players

Dwayne Wysinger

An 18-year-old who was fatally shot in the Peabody-Darst-Webbe neighborhood of St. Louis in 2021.

St. Louis Metropolitan Police Department (SLMPD)

The law enforcement agency investigating Wysinger's unsolved homicide and renewing its appeal for public information.

U.S. Attorney's Office for the Eastern District of Missouri

The federal prosecutors who reported the 2024 indictments of two St. Louis men on charges related to Wysinger's murder.

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What they’re saying

“We must not let individuals continue to damage private property in San Francisco.”

— Robert Jenkins, San Francisco resident (San Francisco Chronicle)

What’s next

The judge in the case will decide on Tuesday whether or not to allow Walker Reed Quinn out on bail.

The takeaway

This case highlights growing concerns in the community about repeat offenders released on bail, raising questions about bail reform, public safety on SF streets, and if any special laws to govern autonomous vehicles in residential and commercial areas.