Mayo Clinic Proceedings Celebrates 100 Years of Discovery

The renowned medical journal marks a century of advancing scientific knowledge and improving patient care worldwide.

Mar. 24, 2026 at 6:34am

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For 100 years, Mayo Clinic Proceedings has helped shape the course of modern medicine by publishing groundbreaking discoveries that have translated from the page to the bedside and improved care for patients around the world. As the journal approaches its centennial in April 2026, Mayo Clinic is celebrating the milestone with events, exhibitions, and special publications that showcase a century of scientific rigor, collaboration, and impact.

Why it matters

Mayo Clinic Proceedings has been at the forefront of medical research and innovation since its inception in 1926. The journal's commitment to publishing content that informs, inspires, and advances healthcare has made it an internationally renowned and influential publication, ranking among the top 10% of general and internal medicine journals globally.

The details

First published in April 1926 as the Bulletin of the Mayo Clinic and Mayo Foundation, Mayo Clinic Proceedings has evolved from an internal newsletter to a leading journal of general and internal medicine that reaches millions of readers worldwide. In 2025, the journal had more than 7 million article downloads and a journal Impact Factor of 6.7. Since January 2025, the journal has been highlighting its 100-year commitment to research that has transformed medical science and practice, and on April 25, a centennial reception will be held on the Rochester campus.

  • Mayo Clinic Proceedings was first published in April 1926.
  • In 2025, the journal had more than 7 million article downloads and a journal Impact Factor of 6.7.
  • Since January 2025, the journal has been highlighting its 100-year commitment to research.
  • On April 25, 2026, a centennial reception will be held on the Rochester campus.

The players

Mayo Clinic Proceedings

A leading journal of general and internal medicine that reaches millions of readers worldwide and ranks among the top 10% of general and internal medicine journals internationally.

Karl Nath, M.B., Ch.B., M.D.

The editor-in-chief of Mayo Clinic Proceedings, who says the journal's spirit and intent have always been expansive, committed to sharing knowledge, educating, and improving care.

William A. Mayo, M.D.

One of the Mayo brothers who, in the 1920s, sat in the front row of weekly staff meetings at Mayo Clinic, where colleagues presented cases and discussed new approaches to patient care.

Charles W. Mayo, M.D.

One of the Mayo brothers who, in the 1920s, sat in the front row of weekly staff meetings at Mayo Clinic, where colleagues presented cases and discussed new approaches to patient care.

Maude Mellish Wilson

The Mayo Clinic's first institutional librarian, who was enlisted to summarize the weekly staff meetings, which evolved into the Mayo Clinic Proceedings newsletter.

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What they’re saying

“Mayo Clinic Proceedings began as an internal publication, but its spirit and intent always were expansive. It was meant to share knowledge, to educate and to improve care - values that continue to guide it a century later. As we enter our second century, we remain committed to publishing content that informs, inspires and advances healthcare.”

— Karl Nath, M.B., Ch.B., M.D., Mayo Clinic Proceedings editor-in-chief

What’s next

On April 25, 2026, a centennial reception will be held on the Mayo Clinic's Rochester campus to celebrate the journal's 100-year milestone.

The takeaway

Mayo Clinic Proceedings has been at the forefront of medical research and innovation for the past century, publishing groundbreaking discoveries that have transformed medical science and practice and improved patient care worldwide. The journal's commitment to sharing knowledge, educating, and advancing healthcare continues to guide it as it enters its second century.