OneMedNet Reports Robust 2025 Financials, Advances AI-Powered iRWD Platform

Subscription-based model drives revenue growth, reduces liabilities, and expands real-world data network

Apr. 6, 2026 at 1:16pm

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OneMedNet, a leading provider of regulatory decision-grade, AI-driven real-world data (RWD), reported strong 2025 financial results, including a 329% year-over-year increase in RWD revenue, a 74% reduction in total liabilities, and continued commercial momentum driven by its Palantir Foundry-powered iRWD platform. The company is transitioning to a scalable, subscription-based model and expects further growth in 2026 as it expands its provider network and data scale.

Why it matters

OneMedNet's performance highlights the growing demand for real-world data and analytics to power healthcare innovation. As the company transitions to a subscription model and enhances its AI-driven platform, it is positioning itself to be a key player in the rapidly evolving real-world data landscape, which is critical for drug development, medical device innovation, and the advancement of AI-powered healthcare solutions.

The details

OneMedNet's 2025 financial highlights include a 329% year-over-year increase in RWD revenue, from $292,000 in 2024 to $1,254,000 in 2025. The company also saw a surge in fourth-quarter revenue, reaching over $890,000. This revenue growth is beginning to align with previously disclosed increases in bookings, reinforcing OneMedNet's transition to a scalable, subscription-based model. Additionally, the company reduced its total liabilities by 74%, from $19.7 million at the end of 2024 to $5.1 million at the end of 2025, through negotiated settlements and debt-to-equity conversions. This has substantially improved the company's equity position, reducing the shareholder deficit from $16.0 million to $3.0 million.

  • OneMedNet reported its 2025 financial results on April 6, 2026.
  • The company's fourth-quarter revenue surge occurred in the quarter ended December 31, 2025.
  • OneMedNet announced its new commercial phase centered on the AI-driven iRWD platform in February 2026.

The players

OneMedNet Corporation

A leading provider of regulatory decision-grade, AI-driven real-world data (RWD) solutions.

Aaron Green

CEO and President of OneMedNet Corporation.

Palantir Foundry

The AI-powered data platform that enables OneMedNet's conversational search on real-time medical data.

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What they’re saying

“Our 2025 performance marks a pivotal turning point for OneMedNet. We have successfully sunset our BEAM solution along with the expenses associated with it, allowing us to focus fully on our Real-World Data business achieving meaningful revenue acceleration, dramatically improving our balance sheet, and launching the next generation of our platform. We believe the early response from customers validates our strategy — delivering real-world data with the speed, scale, and intelligence required to power modern healthcare innovation.”

— Aaron Green, CEO & President

What’s next

OneMedNet expects to add 2 pilot customers in contracting and 4 additional customers representing seven-figure subscription revenue potential in the second and third quarters of 2026. The company also has an advanced stage pipeline of additional multi-year subscription opportunities.

The takeaway

OneMedNet's strong 2025 financial performance, driven by its transition to a scalable, subscription-based model and the launch of its AI-powered iRWD platform, positions the company as a key player in the rapidly evolving real-world data landscape, which is critical for powering healthcare innovation and disruption.