Cholecystectomy Outcomes Improve Despite Patient Complexity

Rates of complications like bile duct injury and hemorrhage decline over a decade among Medicare inpatients

Mar. 18, 2026 at 4:19am

A retrospective study of Medicare beneficiaries who underwent minimally invasive cholecystectomy from 2011 to 2021 found that surgical safety improved substantially, with rates of complications such as bile duct injury and intraoperative hemorrhage decreasing. However, the use of postoperative percutaneous drainage and endoscopic retrograde cholangiopancreatography (ERCP) increased notably during this period.

Why it matters

Cholecystectomy is a common operation, with overall morbidity reported at 10%-20% and bile duct injury occurring in approximately 0.3% of patients. This study provides important longitudinal data on outcomes in inpatients undergoing minimally invasive cholecystectomy in the US, highlighting progress made through surgical quality improvement efforts.

The details

The researchers analyzed Medicare fee-for-service claims data from 2011 to 2021, including 516,372 Medicare beneficiaries (mean age, 74.8 years; 52.4% female) who underwent minimally invasive cholecystectomy. They found that adjusted rates of overall complications decreased from 21.5% in 2011 to 16.5% in 2021, and serious complications declined from 12.3% to 7.0% during the same period. Rates of intraoperative hemorrhage, blood transfusion, and bile duct injury also decreased significantly. However, the use of postoperative percutaneous drainage and ERCP within 1 year increased.

  • The study period was from 2011 to 2021.
  • The researchers analyzed data from 2011 to 2021.

The players

Cody Lendon Mullens

The lead author of the study, affiliated with the University of Michigan, Ann Arbor.

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What’s next

The authors suggest that future initiatives should focus on understanding the growing use of postoperative percutaneous drainage and ERCP to continue improving the safety of cholecystectomy.

The takeaway

This study highlights the progress made in improving the safety of minimally invasive cholecystectomy for Medicare inpatients, with decreases in overall and serious complications. However, the increased use of postoperative percutaneous drainage and ERCP suggests the need for further quality improvement efforts in this area.