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Waltham Today
By the People, for the People
Boothbay Fund Management Boosts Stake in Syndax Pharmaceuticals
Institutional investor increases position in biotech company by over 100%
Mar. 16, 2026 at 7:53am
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Boothbay Fund Management LLC has significantly increased its stake in Syndax Pharmaceuticals, Inc. (NASDAQ:SNDX), a clinical-stage biopharmaceutical company focused on developing novel cancer therapies. According to a recent SEC filing, the institutional investor boosted its position in Syndax by 103.3% in the third quarter, now owning 261,933 shares worth approximately $4 million.
Why it matters
Syndax Pharmaceuticals is a promising biotech company working on innovative cancer treatments, and increased investment from institutional investors like Boothbay Fund Management suggests growing confidence in the company's pipeline and future prospects. This news could signal positive momentum for Syndax as it continues advancing its clinical programs.
The details
Boothbay Fund Management's increased stake in Syndax Pharmaceuticals comes as the biotech company has been making progress with its lead investigational candidate, entinostat, a selective class I histone deacetylase (HDAC) inhibitor being evaluated for multiple solid tumor and hematologic indications. Syndax has also been expanding its research platform aimed at enhancing the effectiveness of existing cancer therapies and addressing high unmet medical needs.
- Boothbay Fund Management increased its position in Syndax Pharmaceuticals by 103.3% in the 3rd quarter of 2026.
The players
Boothbay Fund Management LLC
An institutional investor that has significantly increased its stake in Syndax Pharmaceuticals, now owning 261,933 shares worth approximately $4 million.
Syndax Pharmaceuticals, Inc.
A clinical-stage biopharmaceutical company dedicated to developing novel cancer therapies, with a focus on its lead investigational candidate entinostat.
The takeaway
Boothbay Fund Management's increased investment in Syndax Pharmaceuticals suggests growing confidence in the biotech company's pipeline and future potential, as it continues advancing its innovative cancer treatments through clinical development.

