LabXchange360 Launches Interoperable Platform to Solve Lab Revenue Issues

New platform ensures lab orders are policy-aligned, financially ready, and validated before testing begins

Published on Feb. 12, 2026

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LabXchange360 has officially launched a new approach to laboratory operations that helps labs solve financial and operational issues before testing begins. The platform integrates with EHRs, ordering portals, LIS, billing systems, and payer data sources to validate, enrich, and orchestrate order data in real-time, ensuring every order enters the lab ecosystem aligned with valid coverage rules, policy requirements, and operational standards.

Why it matters

For too long, laboratories have had to deal with revenue and policy-related challenges after the damage is already done. LabXchange360 aims to flip that model by addressing interoperability, policy alignment, and financial readiness upfront, giving labs smarter, more predictable ways to operate and grow their business.

The details

LabXchange360 delivers a modular, interoperable product suite that includes order verification and validation, payer and medical policy alignment, financial readiness and risk visibility, workflow orchestration and interoperability, and business intelligence and analytics. By combining clean verification, data integrity, intelligent workflow management, and business intelligence, LabXchange360 gives lab leaders clear visibility into performance and financial exposure, driving stronger margins.

  • LabXchange360 officially launched on February 4, 2026.

The players

LabXchange360

A new platform that helps laboratories ensure orders are right before testing begins, powering the next generation of laboratory operations.

John Donnelly

The CEO of LabXchange360 and a pioneer in healthcare data interoperability, who previously founded TeraHealth, an early leader in electronic eligibility and EDI standards.

FrontRunnerHC

The company that provides the data and real-time payer and policy intelligence that informs LabXchange360's platform.

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What they’re saying

“For too long, laboratories have been forced to deal with revenue and policy-related challenges after the damage is already done. LabXchange360 flips that model. By addressing interoperability, policy alignment, and financial readiness, we give labs smarter, more predictable ways to operate and grow.”

— John Donnelly, CEO, LabXchange360

The takeaway

LabXchange360's interoperable platform aims to modernize laboratory operations by addressing key financial and operational issues upfront, giving labs greater confidence, predictability, and margin protection as they work to grow their business.