Cardinals host Red Sox in weekend series

St. Louis looks to continue hot start at home against struggling Boston squad

Apr. 10, 2026 at 4:00pm

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A cubist, fragmented painting depicting a baseball game between the St. Louis Cardinals and Boston Red Sox, with sharp, overlapping geometric shapes in the teams' official colors.The historic rivalry between the Cardinals and Red Sox is deconstructed into a dynamic, geometric visual representation of their upcoming weekend series.Boston Today

The St. Louis Cardinals will welcome the Boston Red Sox to Busch Stadium on Friday night to open a three-game weekend series. The Cardinals enter the matchup at 7-5 overall and 4-2 at home, while the Red Sox have struggled to a 4-8 record so far this season, including just 1-5 on the road.

Why it matters

This early-season series between two historic MLB franchises provides an opportunity for the Cardinals to continue their strong start at home and build momentum, while the Red Sox look to turn around their slow beginning to the year.

The details

St. Louis will send right-hander Dustin May to the mound, while Boston will counter with Connelly Early. The Cardinals have hit 13 home runs so far, putting them among the league leaders, led by the production of Jordan Walker (5 HR, 12 RBIs) and Nolan Gorman (5 RBIs in last 10 games). For the Red Sox, Ceddanne Rafaela has driven in 4 runs and Wilyer Abreu has been a bright spot offensively over the last 10 games.

  • The series opener is scheduled for Friday, April 10, 2026 at 7:15 PM local time.
  • Pregame coverage on KTLO AM 1240 will begin at 6:20 PM.

The players

Dustin May

The starting pitcher for the St. Louis Cardinals in the series opener.

Connelly Early

The starting pitcher for the Boston Red Sox in the series opener.

Jordan Walker

A key offensive contributor for the Cardinals, leading the team with 5 home runs and 12 RBIs.

Nolan Gorman

The Cardinals' second baseman has driven in 5 runs over the last 10 games.

Ceddanne Rafaela

The Red Sox outfielder has driven in 4 runs so far this season.

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What’s next

The series will continue on Saturday and Sunday, with the Cardinals looking to take the series and the Red Sox aiming to bounce back.

The takeaway

This weekend matchup between the Cardinals and Red Sox features two teams heading in opposite directions early in the 2026 season, setting the stage for an intriguing series as St. Louis looks to protect its home field advantage and Boston searches for answers to get its season back on track.