Trump Adviser Warns of Possible Israel Nuclear Escalation in Iran Conflict

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David Sacks, who served as President Donald Trump's czar for artificial intelligence and cryptocurrency, warned in a podcast interview that Israel could potentially use a nuclear weapon in the ongoing conflict with Iran. Sacks cautioned about the risks of an "escalatory approach" in the war, stating that Israel "could just be destroyed" if the conflict continues for weeks or months, and that the use of a nuclear weapon by Israel would be "truly catastrophic."

Why it matters

The conflict between the U.S., Israel, and Iran has already led to civilian and military casualties, disruptions to travel and oil prices, and growing divisions within the U.S. public. Sacks's remarks about the possibility of nuclear escalation by Israel have prompted concern and debate, as the war continues with no clear end in sight.

The details

In the podcast interview, Sacks said there is a "faction of people," largely in the Republican Party, who want the war with Iran to escalate. He warned about the risks to oil and gas infrastructure, water access for neighboring countries, and the potential for continued retaliation from Iran against the Gulf states. Sacks also expressed concern about the damage Israel is already sustaining, stating that "if this war continues for weeks or months, then Israel could just be destroyed." On the possibility of Israel using a nuclear weapon, Sacks said it would be "truly catastrophic" and that there are "a lot of really frightening scenarios about where escalation could lead."

• The conflict between the U.S., Israel, and Iran began in early 2026.
• Sacks made his comments on the podcast All In on March 14, 2026.

What they’re saying

What’s next

It is currently unclear how long the war will last or what the next steps will be, as neither side has signaled a retreat.