Fox Renews 'Best Medicine' for Season 2 After Successful First Season

Josh Charles talks about his role as the straight man in the town of Port Wenn and the show's appeal to audiences.

Apr. 9, 2026 at 12:06am

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An extreme close-up photograph of a luxurious, textured fabric in rich, saturated colors like deep burgundy and gold, capturing the glamour and entertainment industry aesthetic of the 'Best Medicine' TV series.The vibrant textures and colors of the 'Best Medicine' TV series reflect the show's warm, lighthearted tone and appeal to audiences seeking an entertaining escape.Atlanta Today

Fox has renewed the medical comedy series 'Best Medicine' for a second season, just a month before the Season 1 finale aired. The show, which is inspired by the British series 'Doc Martin', has built a healthy audience and found success as the American version of the beloved British show. Lead actor Josh Charles opened up about his role as the straight man in the town full of zany characters, and how the show's warmth and humor have resonated with viewers.

Why it matters

The renewal of 'Best Medicine' for a second season is good news for fans of the show, as it means they can look forward to more episodes of the charming and lighthearted medical comedy. The show's ability to translate the appeal of the British original to American audiences also demonstrates the potential for successful adaptations of beloved international series.

The details

In the first season of 'Best Medicine', Josh Charles has led the cast as the show's straight man, Dr. Martin, whose blood phobia and grounded nature provide a counterpoint to the shenanigans of the quirky residents of Port Wenn. Charles explained that his character is a mix of the straight man and the 'engine' that drives the comedy of the townspeople, with the goal of keeping the characters feeling like real people. The show's renewal for a second season, with a slightly shorter 12-episode run, means fans will get to see more of the developing storylines, including the potential future of Louisa and Mark's relationship, as well as the consequences Martin and Elaine may face for her unlicensed medical assistance.

  • Fox renewed 'Best Medicine' for Season 2 in early March 2026, a full month before the Season 1 finale aired.
  • The second season of 'Best Medicine' is expected to premiere in early 2027, rather than the fall like the first season.

The players

Josh Charles

The lead actor of 'Best Medicine', known for his role in 'The Good Wife', who plays the straight man character of Dr. Martin.

Fox

The television network that airs 'Best Medicine' and has renewed the show for a second season.

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What they’re saying

“I don't know. It's not a question that I really feel like I can answer, because I don't have the magic formula. But I think certainly, around this time in the world, I think just having a show that isn't violent. It's just sort of a place where you could just enjoy sitting with for an hour a week, with warmth and kind of humor and lightness that seems [great.]”

— Josh Charles, Lead Actor, 'Best Medicine'

“It's fun. I mean, I think he's kind of a mixed character, because I think he's part straight man, part kind of the engine that his actions can drive a lot of the townspeople's comedy, and I think he's kind of a bit of a fool at times, and physically. I think it's just trying to ground it in his truth so these all feel like real people.”

— Josh Charles, Lead Actor, 'Best Medicine'

What’s next

Fans can look forward to the return of 'Best Medicine' in early 2027 for a 12-episode second season on Fox, which will continue the storylines and character development from the first season.

The takeaway

The renewal of 'Best Medicine' for a second season demonstrates the show's ability to successfully adapt the charm and appeal of the British series 'Doc Martin' for American audiences, providing a welcome respite from gritty dramas with its warmth, humor, and lighthearted approach to storytelling.