RevGenetics Unveils Absorption-Boosting Berberine Supplement

Miami-based supplement company tackles the "berberine absorption gap" with new enteric-coated formula.

Mar. 20, 2026 at 5:04am

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Miami-based supplement company RevGenetics has launched DiBerberine 300x, an advanced berberine supplement that aims to address the industry-wide "berberine absorption gap." The new formula combines enteric-coated dihydroberberine (DHB) with a patent-pending P-gp efflux modulator, targeting the two main barriers to berberine absorption that most supplements fail to solve.

Why it matters

Berberine is a popular supplement for its potential health benefits, but poor absorption has limited its effectiveness. RevGenetics' new formula tackles this issue by protecting the active compound from stomach acid degradation and enhancing its absorption past the intestinal P-gp efflux pumps.

The details

DiBerberine 300x features an enteric-coated capsule that bypasses the stomach and releases the DHB in the small intestine, preventing it from reverting to standard berberine HCl. The formula also includes a patent-pending flavonoid complex called RGBooster1 that modulates the P-gp active transport mechanism to improve absorption.

  • The DiBerberine 300x supplement was commercially launched in March 2026.

The players

RevGenetics

A Miami-based supplement company that developed the DiBerberine 300x formula.

Anthony Loera

The founder of RevGenetics who led the development of the DiBerberine 300x supplement.

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What they’re saying

“The question we kept asking was: why is the supplement industry selling a mechanism – AMPK activation – with a delivery system that undermines the mechanism?”

— Anthony Loera, Founder, RevGenetics

“Enteric coating isn't new technology. Applying that technology to DHB was the obvious move. It just hadn't been done in a commercially available formula.”

— Anthony Loera, Founder, RevGenetics

The takeaway

RevGenetics' new DiBerberine 300x supplement represents an innovative approach to improving berberine absorption and addressing the limitations of standard berberine supplements on the market. By combining enteric-coated dihydroberberine with a proprietary absorption-boosting complex, the company aims to unlock the full potential of this popular supplement.