New Studies Link Vitamin B to Brain Health

SYNEVIT® reports on research connecting B vitamins to cognitive function and mental health.

Published on Feb. 3, 2026

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Recent studies have found that higher levels of certain B vitamins, like B9 (methyl folate) and B12 (methylcobalamin), are associated with slower cognitive decline and reduced depressive symptoms. SYNEVIT®, a vitamin and supplement company, has developed a comprehensive B-complex formula called NEUROCOMPLEX-B® to address these brain health benefits of B vitamins.

Why it matters

As the population ages, maintaining cognitive function and mental health are growing public health concerns. These new studies suggest that ensuring adequate intake of key B vitamins could be an important strategy for supporting brain health and preventing conditions like dementia and depression.

The details

The first study, published in The Journal of the Alzheimer's Association, found that higher mid-to-late-life B12 status was linked to slower cognitive decline across multiple domains. Another study in November explored the connection between B9, B12, and depression, concluding that deficiencies in these vitamins can exacerbate depressive symptoms due to their roles in neurotransmitter production and neural health.

  • In late October 2025, researchers published a study on the cognitive benefits of higher B12 status.
  • In November 2025, another study explored the link between B9, B12, and depression.

The players

SYNEVIT®

A vitamin and supplement company that has developed a comprehensive B-complex formula called NEUROCOMPLEX-B® to address the brain health benefits of B vitamins.

George Cvetkovski

The CEO of SYNEVIT®, who commented on the company's motivation to create NEUROCOMPLEX-B® based on the growing evidence connecting B vitamins to cognitive function and mental health.

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What’s next

Much still remains to be studied when it comes to B-vitamins and the brain. However, the evidence is mounting that NEUROCOMPLEX-B's active forms of folate and methylfolate, presented in bioavailable, concentrated, slow-release form, are ideal support tools for those looking to prevent depression and manage cognitive decline.

The takeaway

These new studies highlight the important role that B vitamins, particularly B9 and B12, play in supporting brain health and mental well-being. As the population ages, ensuring adequate intake of these key nutrients could be an effective strategy for maintaining cognitive function and preventing conditions like dementia and depression.