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ER Alum Mekhi Phifer Hopes for Cameo in The Pitt with Former Co-Star Noah Wyle
Phifer, who played Dr. Pratt on the hit medical drama, says he'd 'love' to reunite with Wyle on the HBO series.
Jan. 28, 2026 at 1:55pm
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Mekhi Phifer, best known for his role as Dr. Gregory Pratt on the long-running medical drama ER, revealed that he would be open to making a cameo appearance on the HBO series The Pitt, which stars his former ER co-star Noah Wyle. Phifer spoke about the possibility of reuniting with Wyle during an interview at Lifetime's 'Love of a Lifetime' event in Los Angeles.
Why it matters
Phifer and Wyle had great on-screen chemistry during their time on ER, and fans would likely be excited to see the two actors reunite, even if in a different context. A potential cameo could also help drive interest in The Pitt and provide a fun nod to the actors' shared history.
The details
During the interview, Phifer expressed his enthusiasm for the idea, saying 'I would love it. Those [guys] are my old crew, my old guys. I love Noah Wyle, such a talent I loved working with him on 'ER,' we had such a great time. I would definitely do it, just for the fun of it.' Phifer also speculated that his role might be as a patient rather than a doctor, to differentiate it from their ER dynamic.
- Phifer's comments were made during a January 2023 interview at Lifetime's 'Love of a Lifetime' event in Los Angeles.
The players
Mekhi Phifer
An American actor best known for his roles in films like 8 Mile and the TV series ER, where he played Dr. Gregory Pratt.
Noah Wyle
An American actor who starred alongside Phifer on ER, playing Dr. John Carter. Wyle now leads the cast of the HBO series The Pitt.
What they’re saying
“I would love it. Those [guys] are my old crew, my old guys. I love Noah Wyle, such a talent I loved working with him on 'ER,' we had such a great time. I would definitely do it, just for the fun of it.”
— Mekhi Phifer
“I don't know if I would be a doctor. Maybe I, maybe I'd be a patient that has an arc, maybe a few episode arc as a patient, you know, because it'd be kind of weird with both doctors. You know, we work so well together and work so intimately on that show together, and we have so many, so much scenes and dialogue together. So, probably be a patient or something like that. I like that.”
— Mekhi Phifer
What’s next
Fans will have to wait and see if Phifer and Wyle's reunion on The Pitt comes to fruition, but the ER alum seems eager to work with his former co-star again.
The takeaway
Mekhi Phifer's enthusiasm for a potential cameo on The Pitt alongside his ER co-star Noah Wyle highlights the enduring chemistry and fond memories the two actors share from their time on the hit medical drama. A reunion of the two on the HBO series could provide a fun nod to their shared history and delight fans of both shows.
