Nisa Investment Advisors Boosts Amgen Stake by 5.2%

Institutional investor increases holdings in biotech giant amid broader market shifts

Apr. 1, 2026 at 10:34am

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Nisa Investment Advisors LLC, a major institutional investor, has increased its stake in Amgen Inc. (NASDAQ:AMGN) by 5.2% during the fourth quarter of 2025, according to a recent SEC filing. The firm now owns 168,716 shares of the medical research company's stock, valued at $55.22 million.

Why it matters

Amgen is a bellwether biotech company, and changes in major institutional holdings can signal broader trends in the sector and the overall market. This increase by Nisa Investment Advisors suggests confidence in Amgen's long-term prospects, even as the stock has seen volatility amid shifting market conditions.

The details

Nisa Investment Advisors added 8,334 shares to its Amgen position during the fourth quarter, bringing its total holdings to 168,716 shares. The firm's increased stake in Amgen comes as the stock has seen a 12-month trading range between $261.43 and $391.29 per share. Amgen's share price has been impacted by factors like patent expirations, pipeline developments, and broader macroeconomic trends affecting the pharmaceutical industry.

  • Nisa Investment Advisors increased its Amgen stake during the fourth quarter of 2025.
  • Amgen's 52-week trading range has been between $261.43 and $391.29 per share.

The players

Nisa Investment Advisors LLC

A major institutional investor that manages a diversified portfolio of stocks, bonds, and other assets.

Amgen Inc.

A global biotechnology company that focuses on discovering, developing, manufacturing, and delivering human therapeutics to address serious illnesses.

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The takeaway

Nisa Investment Advisors' increased stake in Amgen suggests institutional confidence in the biotech company's long-term prospects, even as the stock has seen volatility amid broader market shifts. This move highlights the importance of monitoring changes in major holdings by institutional investors when analyzing the performance and outlook of key industry players.