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Santa Clara vs Kentucky Odds for March Madness NCAA Tournament Betting
March Madness odds for the first-round matchup between the No. 10 seed Santa Clara Broncos and the No. 7 seed Kentucky Wildcats
Mar. 16, 2026 at 4:54am
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The Kentucky Wildcats are a 4.5-point favorite over the Santa Clara Broncos in the first round of the 2026 NCAA Tournament, according to BetMGM Sportsbook. Kentucky is also listed at -180 on the moneyline, while Santa Clara is at +145. The over/under for the game is set at 160.5 points.
Why it matters
This March Madness matchup between Santa Clara and Kentucky is an intriguing first-round game, with the Wildcats looking to advance as the higher seed while the Broncos aim to pull off an upset. The betting odds provide insight into how oddsmakers view the relative strengths of the two teams heading into the tournament.
The details
BetMGM Sportsbook has set the point spread for the Santa Clara vs Kentucky game at Kentucky -4.5. The Wildcats are the -180 favorites on the moneyline, meaning a $180 bet would win $100, while Santa Clara is the +145 underdog, meaning a $100 bet would win $145. The over/under for the total points scored in the game is 160.5.
- The Santa Clara vs Kentucky NCAA Tournament first-round game will be played on Friday, March 20, 2026.
The players
Santa Clara Broncos
The Santa Clara Broncos are the No. 10 seed in the Midwest Region of the 2026 NCAA Tournament.
Kentucky Wildcats
The Kentucky Wildcats are the No. 7 seed in the Midwest Region of the 2026 NCAA Tournament.
What’s next
The winner of the Santa Clara vs Kentucky game will advance to the second round of the 2026 NCAA Tournament.
The takeaway
This first-round March Madness matchup between the Santa Clara Broncos and Kentucky Wildcats features an intriguing clash of styles, with the underdog Broncos looking to pull off an upset over the favored Wildcats. The betting odds suggest Kentucky is the clear favorite, but Santa Clara will be aiming to defy the odds and advance in the NCAA Tournament.
