Domp� Launches Phase 2 Study of Intranasal NGF for Cerebral Palsy

The pharmaceutical company is investigating a new treatment approach for spastic cerebral palsy.

Mar. 30, 2026 at 6:09pm

Domp�, a pharmaceutical company, has announced the enrollment of the first patient in a Phase 2 clinical trial evaluating an intranasal form of Nerve Growth Factor (NGF) as a potential treatment for spastic cerebral palsy (CP). The study is taking place in San Mateo, California.

Why it matters

Cerebral palsy is a lifelong condition that can significantly impact a person's mobility and quality of life. New treatment approaches, like the intranasal NGF being studied by Domp�, could help improve outcomes for those living with cerebral palsy.

The details

The Phase 2 study will assess the safety, tolerability, and efficacy of the intranasal NGF treatment in individuals with spastic cerebral palsy. Domp� is investigating this novel delivery method to potentially improve the treatment's ability to reach the affected areas of the brain and nervous system.

  • The first patient has been enrolled in the Phase 2 study as of March 30, 2026.

The players

Domp�

A pharmaceutical company developing an intranasal form of Nerve Growth Factor (NGF) as a potential treatment for spastic cerebral palsy.

Got photos? Submit your photos here. ›

What’s next

The Phase 2 study is expected to continue enrolling patients and evaluating the intranasal NGF treatment over the next 12-18 months.

The takeaway

This new clinical trial represents an important step forward in exploring innovative treatment approaches for individuals living with the challenges of cerebral palsy. If successful, the intranasal NGF therapy could offer a promising new option to help improve mobility and quality of life for those affected by this condition.