Anthropic Expands San Francisco Footprint with 100,000 SF Lease

AI firm deepens presence in Howard Street corridor with new office space

Apr. 2, 2026 at 8:07pm by Ben Kaplan

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A high-end, photorealistic studio still-life photograph featuring a sleek, modern desk setup with a laptop, a few geometric office supplies, and a potted plant, arranged elegantly on a clean, monochromatic background using dramatic studio lighting to represent Anthropic's corporate strategy and growth.Anthropic's strategic expansion into new office space along San Francisco's Howard Street corridor reflects the AI firm's continued growth and commitment to the city.San Francisco Today

Anthropic, an artificial intelligence company, has leased approximately 100,000 square feet of office space at 400 Howard Street in San Francisco. This latest transaction is part of Anthropic's long-term commitment to scaling its operations in the city, further consolidating its cluster of offices within the Howard Street corridor.

Why it matters

Anthropic's expansion in San Francisco's central business district underscores the continued importance of large technology and AI companies in shaping the city's office leasing landscape, even as many office assets grapple with elevated vacancy and evolving workplace strategies.

The details

The 370,000-square-foot building at 400 Howard Street is part of the Foundry Square complex and is owned by the State Teachers Retirement System of Ohio. Anthropic's new lease at 400 Howard Street comes in addition to the company's full-building lease at 300 Howard Street and existing operations at 500 and 505 Howard Street, consolidating Anthropic's presence in the immediate area.

  • Anthropic leased approximately 100,000 square feet at 400 Howard Street in 2026.
  • Earlier in 2026, Anthropic leased the full 300 Howard Street building.
  • Anthropic already maintains operations at 500 and 505 Howard Street, with leases expected to run through 2028.

The players

Anthropic

An artificial intelligence firm that is expanding its footprint in San Francisco's Howard Street corridor.

State Teachers Retirement System of Ohio

The owner of the 400 Howard Street building, which Anthropic has now leased a significant portion of.

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What they’re saying

“The lease at 400 Howard Street is part of Anthropic's long-term commitments as it continues to scale in San Francisco.”

— Anthropic Spokesperson

What’s next

Anthropic is expected to activate the 400 Howard Street space for its workforce before moving into the 300 Howard Street building, further consolidating its operations in the immediate area.

The takeaway

Anthropic's expansion along the Howard Street corridor demonstrates the continued importance of large technology and AI companies in driving office leasing activity in San Francisco, even as the city's office market navigates evolving workplace trends.