Ozempic Users Advised to Moderate Alcohol Intake, Especially During Carnival

Experts warn of increased risks when combining weight loss medication with alcohol and heat exposure

Published on Feb. 14, 2026

For individuals taking semaglutide (Ozempic) for weight management, experts emphasize the importance of moderation when it comes to alcohol consumption, particularly during events like Carnival where several factors can converge to increase risk. While there is no formal prohibition against drinking alcohol while on these medications, the combination of Ozempic, alcohol, heat exposure, and irregular hydration can lead to unpredictable effects and potential complications.

Why it matters

Ozempic, a popular weight loss medication, can have unpredictable interactions with alcohol, and events like Carnival present a unique set of circumstances that can amplify the potential risks. Understanding these risks is crucial for individuals seeking to manage their weight and health while also enjoying social events.

The details

Ozempic, a GLP-1 receptor agonist, works by slowing down the digestive process, which can have unpredictable effects on alcohol absorption. Because the medication delays gastric emptying, alcohol remains in the digestive tract for a longer period, leading to a more significant impact on the body. Events like Carnival, with prolonged exposure to heat, irregular hydration, extended periods without food, and increased alcohol consumption, can create a scenario that exacerbates unpleasant and potentially dangerous effects.

  • As of June 19, 2025, the FDA-approved drug label for semaglutide does not include any specific warnings about drinking alcohol while taking the medication.

The players

Dr. Diana Thiara

Medical director of the University of California San Francisco Weight Management Clinic.

Cynthia Valério

Director of the Brazilian Association for the Study of Obesity and the Metabolic Syndrome.

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What they’re saying

“There is no interaction between alcohol and semaglutide products like Ozempic, however, your body's response to alcohol may be different while on the medication. You may feel the effects more strongly, especially if you have lost a significant amount of weight or are not eating as much as you used to.”

— Dr. Diana Thiara, Medical director of the University of California San Francisco Weight Management Clinic

“There is no formal contraindication to the consumption of alcohol, but greater moderation is recommended.”

— Cynthia Valério, Director of the Brazilian Association for the Study of Obesity and the Metabolic Syndrome

What’s next

Individuals with a history of alcohol or drug dependence should discuss their concerns with a healthcare provider, as there is growing evidence that semaglutide can affect a person's interest in drinking alcohol, and this could present unexpected challenges for those in recovery.

The takeaway

For Ozempic users, moderation is key when it comes to alcohol consumption, especially during events like Carnival where heat exposure, irregular hydration, and increased alcohol intake can amplify the potential risks. Prioritizing overall health and well-being should remain the primary focus, and open communication with a healthcare provider is crucial to assess individual risk factors and develop a safe and informed approach.