Niagen Bioscience Establishes First USP Monograph for Nicotinamide Riboside Chloride

Collaboration with USP sets new industry standard for NR supplement ingredient.

Apr. 9, 2026 at 2:23pm

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A highly textured, abstract painting in muted earth tones featuring sweeping geometric shapes and botanical spirals, conceptually representing the molecular structure and chemical properties of the nutritional compound nicotinamide riboside.A new industry standard for nicotinamide riboside supplements aims to ensure consistent quality and safety for consumers.Los Angeles Today

Niagen Bioscience, a leading manufacturer of nicotinamide riboside (NR) supplements, has announced a collaboration with the United States Pharmacopeia (USP) to establish the first-ever USP monograph for nicotinamide riboside chloride (NRCl), the active ingredient in Niagen's NR products.

Why it matters

This new USP monograph will set an industry-wide quality standard for NR supplements, ensuring consistent purity, potency, and safety for consumers. As the NR market continues to grow, this milestone collaboration between Niagen and USP will help bring greater transparency and trust to the category.

The details

The USP monograph provides detailed specifications and testing methods to verify the identity, strength, quality, and purity of NRCl. This will enable manufacturers, regulators, and consumers to have confidence in the integrity of NR supplements on the market. Niagen Bioscience played a key role in developing the new USP monograph through its extensive research and data sharing.

  • The USP monograph for NRCl was officially published on April 1, 2026.

The players

Niagen Bioscience

A leading manufacturer of nicotinamide riboside (NR) supplements.

United States Pharmacopeia (USP)

An independent, non-profit organization that sets voluntary public standards for the identity, strength, quality, and purity of medicines, food ingredients, and dietary supplements.

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What they’re saying

“This new USP monograph represents a major milestone for the NR industry, providing a clear quality standard that consumers and brands can trust.”

— Dr. Charles Brenner, Chief Scientific Advisor, Niagen Bioscience

What’s next

Niagen Bioscience plans to update all of its NR supplement products to comply with the new USP monograph standards by the end of 2026.

The takeaway

The establishment of the first USP monograph for nicotinamide riboside chloride is an important step forward in bringing greater transparency and quality assurance to the rapidly growing NR supplements market.