TSC Alliance hosts 25th annual Comedy for a Cure event

The fundraiser for rare disease research will feature top comedians in Irvine, California on April 19.

Apr. 3, 2026 at 1:23pm

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A neon outline illustration of a person laughing, with bright glowing lines tracing the movement and energy of the comedic performance, conceptually representing the joy and energy of a community fundraising event.The TSC Alliance's annual Comedy for a Cure fundraiser brings laughter and hope to the rare disease community.Irvine Today

The TSC Alliance, a nonprofit organization focused on tuberous sclerosis complex (TSC) research and support, is hosting its 25th annual Comedy for a Cure event on April 19 at the Irvine Improv in Irvine, California. The fundraiser will feature performances from top comedians to raise money for TSC research and patient programs.

Why it matters

Comedy for a Cure is the TSC Alliance's largest annual fundraising event, providing critical funding for research into TSC, a rare and complex genetic disorder that causes non-cancerous tumors to form in vital organs. The event helps raise awareness and support for the TSC community.

The details

The 25th annual Comedy for a Cure will take place on Sunday, April 19 at the Irvine Improv comedy club in Irvine, California. The event will feature performances from top comedians to entertain attendees and raise money for the TSC Alliance's programs.

  • The TSC Alliance announced the 25th annual Comedy for a Cure on April 3, 2026.
  • The event will be held on Sunday, April 19, 2026.

The players

TSC Alliance

A nonprofit organization focused on supporting research and programs for tuberous sclerosis complex (TSC), a rare genetic disorder.

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What’s next

Tickets for the 25th annual Comedy for a Cure event are on sale now through the Irvine Improv website.

The takeaway

The TSC Alliance's long-running Comedy for a Cure event continues to be an important fundraiser that supports critical research and programs for the TSC community.