Former Orioles Slugger Trey Mancini Signs Minor League Deal with Angels

Mancini, a cancer survivor, looks to make another comeback attempt with the Los Angeles club.

Feb. 4, 2026 at 6:55pm

Trey Mancini, the former Baltimore Orioles slugger and cancer survivor, has agreed to a minor league contract with the Los Angeles Angels that includes an invitation to their big league spring training camp. Mancini is looking to make another attempt at a major league comeback after his previous battles with the disease.

Why it matters

Mancini's story of perseverance and resilience in the face of his cancer diagnosis and treatment has made him a beloved figure in the baseball world. His potential return to the majors with the Angels would be an inspiring comeback tale for fans.

The details

The 31-year-old Mancini last played in the majors in 2022 with the Houston Astros. He was diagnosed with stage 3 colon cancer in 2020 but returned to play later that year. Mancini won the American League Comeback Player of the Year award in 2021 after hitting .255 with 21 home runs and 71 RBIs for the Orioles.

  • Mancini last played in the majors in 2022 with the Houston Astros.
  • Mancini was diagnosed with stage 3 colon cancer in 2020 but returned to play later that year.
  • Mancini won the American League Comeback Player of the Year award in 2021.

The players

Trey Mancini

A former Baltimore Orioles slugger and cancer survivor who is looking to make another comeback attempt with the Los Angeles Angels.

Los Angeles Angels

The Major League Baseball team that has signed Trey Mancini to a minor league contract with an invitation to their big league spring training camp.

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What’s next

Mancini will report to the Angels' spring training camp in Arizona to compete for a spot on the major league roster.

The takeaway

Mancini's potential return to the majors with the Angels would be an inspiring comeback tale for fans, showcasing the power of determination and the human spirit to overcome adversity.