Biological Evidence Found at Nancy Guthrie's Home Analyzed by Investigators

DNA profiles collected from the evidence were put under lab analysis, authorities say.

Published on Feb. 23, 2026

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Investigators in Tucson, Arizona, are analyzing biological evidence found at the home of 84-year-old Nancy Guthrie, who went missing on February 1. The Pima County Sheriff's Department said DNA collected from the evidence was put through lab analysis, though the results of that analysis have not yet been disclosed. Authorities also noted that DNA from a set of gloves found near Guthrie's home did not produce a match in the CODIS database.

Why it matters

The discovery of biological evidence at Guthrie's home could provide crucial clues about what happened to the missing woman. Investigators are leaving no stone unturned as they work to determine Guthrie's whereabouts and the circumstances surrounding her disappearance, which has generated over 18,000 tips to the FBI.

The details

Biological evidence collected from Guthrie's home could include hair, skin, sweat, blood, or other bodily fluids. Authorities previously revealed that DNA from a set of gloves found approximately two miles from Guthrie's home did not match any profiles in the CODIS database, a national DNA index system. The Pima County Sheriff's Department has also stated that none of Guthrie's family members are considered suspects in her disappearance.

  • Nancy Guthrie was reported missing from her home on February 1, 2026.
  • On February 18, 2026, investigators announced they were analyzing biological evidence found at Guthrie's home.

The players

Pima County Sheriff's Department

The law enforcement agency investigating Nancy Guthrie's disappearance.

Nancy Guthrie

An 84-year-old woman who went missing from her Tucson-area home on February 1, 2026.

Chris Nanos

The Pima County Sheriff who stated that none of Guthrie's family members are considered suspects in her disappearance.

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What they’re saying

“Not one single person in the family is a suspect.”

— Chris Nanos, Pima County Sheriff (fox10tv.com)

“We talked to them. We took their phones. We took their computers. We did everything. We processed their vehicles. We processed their homes. They have been really... they're victims.”

— Chris Nanos, Pima County Sheriff (fox10tv.com)

What’s next

Investigators will continue to analyze the biological evidence found at Nancy Guthrie's home in an effort to uncover clues about her disappearance.

The takeaway

The discovery of biological evidence at Guthrie's home underscores the intensive investigation underway to determine what happened to the 84-year-old woman. While authorities have ruled out her family as suspects, the analysis of this evidence could provide critical insights that help bring Guthrie home safely.